Wetterhahn, K E: search on Z-Library

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1

Theranos Experience Exposes Weaknesses in FDA Regulatory Discretion

Jotwani, Rohan, Boumil, Marcia, Salem, Deeb, Wetterhahn, Madeline, Beninger, Paul

Journal:

Clinical Pharmacology in Drug Development

Year:

2017

Language:

english

File:

PDF, 100 KB

english, 2017

2

Reduction of Chromium(VI) by Ascorbate Leads to Chromium-DNA Binding and DNA Strand Breaks in Vitro

Stearns, Diane M., Kennedy, Laura J., Courtney, Kevin D., Giangrande, Paloma H., Phieffer, Laura S., Wetterhahn, Karen E.

Journal:

Year:

1995

Language:

english

File:

PDF, 1.80 MB

english, 1995

3

A prediction of chromium(III) accumulation in humans from chromium dietary supplements.

Stearns, D M, Belbruno, J J, Wetterhahn, K E

Journal:

The FASEB Journal

Year:

1995

Language:

english

File:

PDF, 1.51 MB

english, 1995

4

Reaction of chromium(VI) with hydrogen peroxide in the presence of glutathione: reactive intermediates and resulting DNA damage

Aiyar, Jayshree, Berkovits, Holly J., Floyd, Robert A., Wetterhahn, Karen E.

Journal:

Chemical Research in Toxicology

Year:

1990

Language:

english

File:

PDF, 1.18 MB

english, 1990

5

Launch the Intruders: A Naval Attack Squadron in the Vietnam War, 1972 (review)

Wetterhahn, Ralph

Journal:

The Journal of Military History

Year:

2007

File:

PDF, 237 KB

2007

6

[untitled]

Review by: Ralph F. Wetterhahn and Malcolm Muir, Jr.

Journal:

The Journal of Military History

Year:

2007

Language:

english

File:

PDF, 413 KB

english, 2007

7

Differential Effects of Chromium(VI) on Constitutive and Inducible Gene Expression in Chick Embryo Liver In Vivo and Correlation With Chromium(VI)-Induced DNA Damage

Joshua W. Hamilton, Karen E. Wetterhahn

Journal:

Molecular Carcinogenesis

Year:

1989

Language:

english

File:

PDF, 1.22 MB

english, 1989

8

Reaction of Chromium(VI) with Ascorbate Produces Chromium(V), Chromium(IV), and Carbon-Based Radicals

Stearns, Diane M., Wetterhahn, Karen E.

Journal:

Chemical Research in Toxicology

Year:

1994

Language:

english

File:

PDF, 1.53 MB

english, 1994

9

Reduction of carcinogenic chromium(VI) by dehydroascorbate and its decomposition products.

Diane M. Stearns, Karen E. Wetterhahn

Journal:

Journal of Inorganic Biochemistry

Year:

1993

Language:

english

File:

PDF, 77 KB

english, 1993

10

Inhibition of protein synthesis increases the transcription of the phenobarbital-inducible CYP2H1 and CYP2H2 genes in chick embryo hepatocytes

Joshua W. Hamilton, William J. Bement, Peter R. Sinclair, Jacqueline F. Sinclair, Joy A. Alcedo, Karen E. Wetterhahn

Journal:

Archives of Biochemistry and Biophysics

Year:

1992

Language:

english

File:

PDF, 1.23 MB

english, 1992

11

Identification of the Oxidized Products Formed upon Reaction of Chromium(V) with Thymidine Nucleotides

Sugden, Kent D., Wetterhahn, Karen E.

Journal:

Journal of the American Chemical Society

Year:

1996

Language:

english

File:

PDF, 365 KB

english, 1996

12

Modification of chromium(VI)-induced DNA damage by glutathione and cytochromes P-450 in chicken embryo hepatocytes.

Cupo, D. Y., Wetterhahn, K. E.

Journal:

Proceedings of the National Academy of Sciences

Year:

1985

Language:

english

File:

PDF, 1.10 MB

english, 1985

13

Chromium(VI) Toxicity: Uptake, Reduction, and DNA Damage

Standeven, Andrew, Wetterhahn, Karen

Journal:

International Journal of Toxicology

Year:

1989

Language:

english

File:

PDF, 598 KB

english, 1989

14

Microsomal reduction of the carcinogen chromate produces chromium(V)

Jennette, K. Wetterhahn

Journal:

Journal of the American Chemical Society

Year:

1982

Language:

english

File:

PDF, 271 KB

english, 1982

15

Chromium(III) picolinate produces chromosome damage in Chinese hamster ovary cells.

Stearns, D M, Wise, J P, Patierno, S R, Wetterhahn, K E

Journal:

The FASEB Journal

Year:

1995

Language:

english

File:

PDF, 1.43 MB

english, 1995

16

Repair of chromate-induced DNA damage in chick embryo hepatocytes

Cupo, D.Y., Wetterhahn, K.E.

Journal:

Year:

1984

Language:

english

File:

PDF, 487 KB

english, 1984

17

Chromium (VI)-induced DNA damage in chick embryo liver and blood cells in vivo

Hamilton, Joshua W., Wetterhahn, Karen E.

Journal:

Year:

1986

Language:

english

File:

PDF, 433 KB

english, 1986

18

Chromium bound to DNA alters cleavage by restriction endonucleases

Borges, Kim M., Wetterhahn, Karen E.

Journal:

Chemical Research in Toxicology

Year:

1991

Language:

english

File:

PDF, 1.60 MB

english, 1991

19

Solubilization of the carcinogen nickel subsulfide and its interaction with DNA and protein

Lee, Jeffrey E., Ciccarelli, Richard B., Jennette, Karen Wetterhahn

Journal:

Year:

1982

Language:

english

File:

PDF, 1.00 MB

english, 1982

20

Two pathways for chromium(VI)-induced DNA damage in 14 day chick embryos: Cr—DNA binding in liver and 8-0X0-2’-deoxyguanosine in red blood cells

Misra, Manoj, Alcedo, Joy A., Wetterhahn, Karen E.

Journal:

Year:

1994

Language:

english

File:

PDF, 740 KB

english, 1994

21

Reaction of Chromium(VI) with Glutathione or with Hydrogen Peroxide: Identification of Reactive Intermediates and Their Role in Chromium(VI)-Induced DNA Damage

Jayshree Aiyar, Holly J. Berkovits, Robert A. Floyd and Karen E. Wetterhahn

Journal:

Environmental Health Perspectives

Year:

1991

Language:

english

File:

PDF, 515 KB

english, 1991

22

When Thunder Rolled: An F-105 Pilot over North Vietnam (review)

Wetterhahn, Ralph

Journal:

The Journal of Military History

Year:

2003

File:

PDF, 242 KB

2003

23

Inhibition of NF-κB Binding to DNA by Chromium, Cadmium, Mercury, Zinc, and Arsenitein Vitro:Evidence of a Thiol Mechanism

Jennifer A. Shumilla, Karen E. Wetterhahn, Aaron Barchowsky

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 172 KB

english, 1998

24

Heme regulates hepatic 5-aminolevulinate synthase mRNA expression by decreasing mRNA half-life and not by altering its rate of transcription

Joshua W. Hamilton, William J. Bement, Peter R. Sinclair, Jacqueline F. Sinclair, Joy A. Alcedo, Karen E. Wetterhahn

Journal:

Archives of Biochemistry and Biophysics

Year:

1991

Language:

english

File:

PDF, 835 KB

english, 1991

25

EPR Evidence for Chromium(V) Binding to Phosphate and Pyrophosphate: Implications for Chromium(V)−DNA Interactions

Sugden, Kent D., Wetterhahn, Karen E.

Journal:

Inorganic Chemistry

Year:

1996

Language:

english

File:

PDF, 112 KB

english, 1996

26

Methyl Transfer to Mercury Thiolates: Effects of Coordination Number and Ligand Dissociation

Wilker, Jonathan J., Wetterhahn, Karen E., Lippard, Stephen J.

Journal:

Inorganic Chemistry

Year:

1997

Language:

english

File:

PDF, 160 KB

english, 1997

27

Differential binding of chromium(VI) and chromium(III) complexes to salmon sperm nuclei and nuclear DNA and isolated calf thymus DNA

Hneihen, Azzam S., Standeven, Andrew M., Wetterhahn, Karen E.

Journal:

Year:

1993

Language:

english

File:

PDF, 1.06 MB

english, 1993

28

In vitro reaction of the carcinogen chromate with cellular thiols and carboxylic acids

Connett, P. H., Wetterhahn, K. E.

Journal:

Journal of the American Chemical Society

Year:

1985

Language:

english

File:

PDF, 833 KB

english, 1985

29

Arsenic induces oxidant stress and NF-KB activation in cultured aortic endothelial cells

Aaron Barchowsky, Edward J. Dudek, Melinda D. Treadwell, Karen E. Wetterhahn

Journal:

Free Radical Biology and Medicine

Year:

1996

Language:

english

File:

PDF, 1.03 MB

english, 1996

30

Reaction of chromium(VI) with thiols: pH dependence of chromium(VI) thio ester formation

Connett, P. H., Wetterhahn, K. E.

Journal:

Journal of the American Chemical Society

Year:

1986

Language:

english

File:

PDF, 717 KB

english, 1986

31

The genotoxic carcinogen chromium(VI) alters the metal-inducible expression but not the basal expression of the metailothionein gene in vivo

Alcedo, Joy A., Misra, Manoj, Hamilton, Joshua W., Wetterhahn, Karen E.

Journal:

Year:

1994

Language:

english

File:

PDF, 457 KB

english, 1994

32

The interaction of chromium with nucleic acids

Michael J. Tsapakos, Karen E. Wetterhahn

Journal:

Chemico-Biological Interactions

Year:

1983

Language:

english

File:

PDF, 1.04 MB

english, 1983

33

Reduction of chromium(VI) to chromium(V) by rat liver cytosolic and microsomal fractions: is DT-diaphorase involved?

Aiyar, Jayshree, De Flora, Silvio, Wetterhahn, Karen E.

Journal:

Year:

1992

Language:

english

File:

PDF, 4.48 MB

english, 1992

34

Is there a role for reactive oxygen species in the mechanism of chromium(VI) carcinogenesis?

Standeven, Andrew M., Wetterhahn, Karen E.

Journal:

Chemical Research in Toxicology

Year:

1991

Language:

english

File:

PDF, 1.49 MB

english, 1991

35

Ascorbate is the principal reductant of chromium(VI) in rat lung ultrafiltrates and cytosols, and mediates chromium–DNA binding in vitro

Standeven, Andrew M., Wetterhahn, Karen E., Kato, Ryuichi

Journal:

Year:

1992

Language:

english

File:

PDF, 4.37 MB

english, 1992

36

Chromium cross-links glutathione and cysteine to DNA

Borges, Kim M., Wetterhahn, Karen E.

Journal:

Year:

1989

Language:

english

File:

PDF, 420 KB

english, 1989

37

[untitled]

Review by: Ralph F. Wetterhahn

Journal:

The Journal of Military History

Year:

2003

Language:

english

File:

PDF, 313 KB

english, 2003

38

Effect of chromium(III) on poly(dG-dC) conformation

Norman A. Floro, Karen E. Wetterhahn

Journal:

Biochemical and Biophysical Research Communications

Year:

1984

Language:

english

File:

PDF, 402 KB

english, 1984

39

Interlaboratory validation of a new assay for DNA-protein crosslinks

Max Costa, Anatoly Zhitkovich, Michael Gargas, Dennis Paustenbach, Brent Finley, Jim Kuykendall, Ruth Billings, Timothy J. Carlson, Karen Wetterhahn, Jian Xu, Steven Patierno, Matthew Bogdanffy

Journal:

Mutation Research/Genetic Toxicology

Year:

1996

Language:

english

File:

PDF, 641 KB

english, 1996

40

Role of chromium(V), glutathione thiyl radical and hydroxyl radical intermediates in Chromium(VI)‐induced DNA Damage

Aiyar, Jayshree, Borges, Kim M., Floyd, Robert A., Wetterhahn, Karen E.

Journal:

Toxicological & Environmental Chemistry

Year:

1989

Language:

english

File:

PDF, 747 KB

english, 1989

41

Cell-enhanced dissolution of carcinogenic lead chromate particles: the role of individual dissolution products in clastogenesis

Wise, John Pierce, Stearns, Diane M., Wetterhahn, Karen E., Patierno, Steven R.

Journal:

Year:

1994

Language:

english

File:

PDF, 2.42 MB

english, 1994

42

Possible Role of Glutathione in Chromium(VI) Metabolism and Toxicity in Rats

Andrew M. Standeven, Karen E. Wetterhahn

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1991

Language:

english

File:

PDF, 873 KB

english, 1991

43

Chromium(VI) forms a thiolate complex with glutathione

Brauer, Samuel L., Wetterhahn, Karen E.

Journal:

Journal of the American Chemical Society

Year:

1991

Language:

english

File:

PDF, 888 KB

english, 1991

44

Activation of chromium(VI) by thiols results in chromium(V) formation, chromium binding to DNA and altered DNA conformation

Borges, Kim M., Boswell, John S., Liebross, Robert H., Wetterhahn, Karen E.

Journal:

Year:

1991

Language:

english

File:

PDF, 6.00 MB

english, 1991

45

ChemInform Abstract: Reaction of Chromium(VI) with Thiols: pH Dependence of Chromium(VI) Thio Ester Formation

CONNETT, P. H., WETTERHAHN, K. E.

Journal:

Chemischer Informationsdienst

Year:

1986

File:

PDF, 109 KB

1986

46

Mechanism of chromium(VI) carcinogenesis: Reactive intermediates and interaction with DNA

KarenE. Wetterhahn

Journal:

Journal of Inorganic Biochemistry

Year:

1989

Language:

english

File:

PDF, 57 KB

english, 1989

47

The Role of Metals in Carcinogenesis: Biochemistry and Metabolism

K. Wetterhahn Jennette

Journal:

Environmental Health Perspectives

Year:

1981

Language:

english

File:

PDF, 4.06 MB

english, 1981

48

In vivo formation of chromium(V) in chick embryo liver and red blood cells

Liebross, Robert H., Wetterhahn, Karen E.

Journal:

Year:

1992

Language:

english

File:

PDF, 2.90 MB

english, 1992

49

Reaction of chromium(VI) with glutathione or with hydrogen peroxide: identification of reactive intermediates and their role in chromium(VI)-induced DNA damage.

Aiyar, J, Berkovits, H J, Floyd, R A, Wetterhahn, K E

Journal:

Environmental Health Perspectives

Year:

1991

Language:

english

File:

PDF, 1.75 MB

english, 1991

50

Electron-transport cytochrome P-450 system is involved in the microsomal metabolism of the carcinogen chromate

J.D. Garcia, K.Wetterhahn Jennette

Journal:

Journal of Inorganic Biochemistry

Year:

1981

Language:

english

File:

PDF, 1.00 MB

english, 1981

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